Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
Identifieur interne : 001A13 ( Main/Exploration ); précédent : 001A12; suivant : 001A14Memantine for patients with Parkinson's disease dementia or dementia with Lewy bodies: a randomised, double-blind, placebo-controlled trial.
Auteurs : Murat Emre [Turquie] ; Magda Tsolaki ; Ubaldo Bonuccelli ; Alain Destée [France] ; Eduardo Tolosa ; Alexandra Kutzelnigg ; Andrés Ceballos-Baumann ; Slobodan Zdravkovic ; Anna Bladström ; Roy JonesSource :
- The Lancet. Neurology [ 1474-4465 ] ; 2010.
Descripteurs français
- Wicri :
- geographic : Turquie.
English descriptors
- KwdEn :
- Accidental Falls (prevention & control), Aged, Aged, 80 and over, Dementia (drug therapy), Dementia (psychology), Double-Blind Method, Europe, Female, Humans, Internationality, Lewy Body Disease (drug therapy), Lewy Body Disease (psychology), Male, Memantine (adverse effects), Memantine (therapeutic use), Parkinson Disease (drug therapy), Parkinson Disease (psychology), Sleep Stages (drug effects), Turkey.
- MESH :
- chemical , adverse effects : Memantine.
- chemical , therapeutic use : Memantine.
- geographic : Europe, Turkey.
- drug effects : Sleep Stages.
- drug therapy : Dementia, Lewy Body Disease, Parkinson Disease.
- prevention & control : Accidental Falls.
- psychology : Dementia, Lewy Body Disease, Parkinson Disease.
- Aged, Aged, 80 and over, Double-Blind Method, Female, Humans, Internationality, Male.
Abstract
Previous studies have suggested that patients with Lewy-body-related dementias might benefit from treatment with the N-methyl D-aspartate receptor antagonist memantine, but further data are needed. Therefore, the efficacy and safety of memantine were investigated in patients with mild to moderate Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB).
Url:
DOI: 10.1016/S1474-4422(10)70194-0
PubMed: 20729148
Affiliations:
- France, Turquie
- Hauts-de-France, Nord-Pas-de-Calais
- Lille
- Université Lille 2, Université Lille Nord de France
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: 000A38
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Previous studies have suggested that patients with Lewy-body-related dementias might benefit from treatment with the N-methyl D-aspartate receptor antagonist memantine, but further data are needed. Therefore, the efficacy and safety of memantine were investigated in patients with mild to moderate Parkinson's disease dementia (PDD) or dementia with Lewy bodies (DLB).</div>
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